Thank you for a nice post. Seems that I don't understand the free drug hypothesis enough, and don't get the point of the example from PLK1 paper, but what is wrong with the attempt to reduce the binding to plasma proteins?:) Thanks in advance for any clarification
Thank you for a nice post. Seems that I don't understand the free drug hypothesis enough, and don't get the point of the example from PLK1 paper, but what is wrong with the attempt to reduce the binding to plasma proteins?:) Thanks in advance for any clarification
See the post below, where I write about this at great length.
https://krhornberger.substack.com/p/tweetorial-free-drug-hypothesis
thanks!